Dr. Tatomir Corina - Bianca

Specialitatea şi supraspecialitatea:   Chimie si Biochimie medicala
Poziţia curentă:   Chimist principal in cadrul Laboratorului de Radiobiologie si Biologie Tumorala
Contact  Email:coratat@yahoo.com
Competenţe:  ● Scoala de vara nationala “ Genomica functionala in Terapia si Biologia Cancerului”, Cluj-Napoca, 2016
● Curs de perfectionare “New technologies in clinical radiation oncology: implementation in Romania”, UMF, Cluj-Napoca, 2016
● Curs “Advances in Molecular Targeted Therapy”, UMF Cluj-Napoca, 2013
Domeniul de interes în cercetare:  - Efectul antioxidant si antitumoral al unor produsi naturali
- Terapia fotodinamica in diferite localizari si biocompozite
- Fotochemopreventia in cancerul pielii cu produsi naturali
- Apotoza si angiogeneza tumorilor
- Evaluarea leziunilor ADN
- Studiul metaloproteinazelor in culturi de celule si in tumori mamare, digestive, ovariene
- Identificare proteine prin western blot
Studii: Universitatea Babes-Bolyai, Licenta in Tehnologia substantelor organice
Activitate profesională:  - teste pe culturi de celule, teste MTT, VAnexin / PI,- cultivare, caracterizare celule, studii de chimiosensibilitate, chimiorezistenta,- determinari de stres oxidativ,- izolare si determinare cantitativa de proteine prin ELISA,- spectrofotometrie, electroforeza, Western blot,- mecanisme moleculare in radiobiologie si aplicatiile lor in tratamentele cancerului
Premii:  -OSIM patent nr.127720: Gel fotochemoprotectiv si procedura de obtinere, -OSIM patent nr.127719: Crema fotochemoprotectiva si procedura de obtinere
Publicatiile cele mai importante:
1. Decean H, Perde-Schrepler M, Tatomir C, Fischer-Fodor E, Brie I, Virag P. Modulation of the pro-inflammatory cytokines and matrix metalloproteinases production in co-cultivated human keratinocytes and melanocytes. Arch Dermatol Res. 2013 Oct;305(8):705-14.
2. Popescu T, Nenu I, Aldea MD, Oltean D, Gheba D, Tatomir C et al. The effect of TSPP-mediated photodynamic therapy and Parecoxib in experimental tumours. Life Sciences xxx (2014).
3. Virag P, Brie IC, Burz CC, Tatomir CB et al. Modulation of the UVB-induced Oxidative Stress and Apoptosis in HaCat Cell Line with Calluna Vulgaris Extract, Not Bot Horti Agrobo, 2015, 43(2),:313-319.
4. Opris R, Tatomir C, Olteanu D, Moldovan R et al. The effect of Sambucus nigra L. extract and phytosinthesized gold nanoparticles on diabetic rats.Colloids and Surface B Biointerfaces, 2017, 150, 192-200.
5. Decean H, Perde-Schrepler M, Tatomir C, Fischer-Fodor E, Brie I, Virag P. Modulation of the pro-inflammatory cytokines and matrix metalloproteinases production in co-cultivated human keratinocytes and melanocytes. Arch Dermatol Res. 2013 Oct;305(8):705-14. doi: 10.1007/s00403-013-1353-6. Epub 2013 Apr 20.