Dr. Cherecheş Gabriela Irina


Specialitatea şi supraspecialitatea:  medic primar laborator clinic
Poziţia curentă: Medic primar laborator clinic in Laboratorul de Radiobiologie si Biologie Tumorala
Titluri ştiinţifice: Asistent cercetare
Telefon de contact: Prin centrală, interior 145,174
Competenţe: 02.2004: Curs de perfectionare cu titlul “ Diagnosticul de laborator al hemopatiilor maligne prin citometrie in flux" Bucuresti
09.2006: Curs de perfectionare cu tema " New technologies in clinical radiation oncology: implementation in Romania" Institutul Oncologic „Prof.Dr.I.Chiricuta”, Cluj-Napoca
07. 2006: Scoala de vara - organizata in cadrul proiectului CEEX, BIOGENERO: Genomica Functionala in Terapia si Biologia Cancerului – Institutul Oncologic „Prof.Dr.I. Chiricuta”, Cluj-Napoca
10.2014 : Certificat de absolvire al cursului national " Curs precongres SRROM cu tema: Actualitati in terapia moleculara tintita" UMF "Iuliu Hatieganu" Cluj-Napoca
06.2015 : Certificat de absolvire al cursului de perfectionare " Progrese in Tratamentul Multidisciplinar al Cancerului" desfasurat de discoplina de Oncologie Medicala si Radioterapie a UMF "Iuliu Hatieganu" Cluj-Napoca
10.2017 : Curs de perfectionare cu tema " Actualitati in terapia moleculara tintita si imunologie" ; disciplina de Oncologie Medicala si Radioterapie a UMF "Iuliu Hatieganu" Cluj-Napoca
 
Domeniul de interes în cercetare:  Efecte antioxidative si antitumorale ale unor produsi naturali in vitro
 Terapie fotodinamica in vitro
 Biomarkeri de prognostic si raspuns la tratament ai tumorilor
 Fotochemopreventia cancerului cutanat cu produsi naturali
 Nanotechnologii si biomateriale noi – implicatii in oncologie
 Izolarea si identificarea celulelor tumorale circulante (CTCs) in diverse localizari
 
Studii: 1988-1994 Facultatea de Medicina si Farmacie, sectia Medicina Generala, promotia 1994
1996-2003: Rezidentiat in medicina de laborator
2003-2016: Medic specialist laborator clinic
2016-prezent : Medic primar laborator clinic
Activitate profesională: • elaborarea si participarea la proiecte de cercetare stiintifice nationale si internationale.
• diseminarea rezultatelor obtinute la diverse manifestari stiintifice nationale si internationale; participari la congrese, conferinte, simpozioane, workshop-uri, seminarii si alte evenimente stiintifice
• activitati in laborator: initierea, intretinerea si propagarea unor culturi de celule primare si linii celulare, normale si tumorale; separarea celulelor sanguine din sange integral; teste citogenetice; teste de radio- si chimiosensibilitate in vitro; teste de citotoxicitate; teste de apoptoza; teste de evaluare a stresului oxidativ; determinarea unor proteine/molecule cu tehnica ELISA; izolarea si identificarea celulelor tumorale circulante; izolarea, cultivarea si caracterizarea celulelor stem tumorale
 
Premii: Diploma de excelenta si medalia de aur – A.Filip, M.Achim, I.D.Postescu, M.Perde-Schrepler, D.Daicoviciu, A.Muresan, C.Tatomir, G.Chereches, S.Suciu, S.Clichici, P.Virag, E.Fischer-Fodor, O.Soritau, R.Moldovan, I.Brie, T.Dicu – pentru preparate farmaceutice cu efecte fotochemprotectoare - Salonul International de Inventica, PRO INVENT, editia a IX-a, 2011, Cluj-Napoca.
OSIM patent nr.127720: Gel fotochemoprotector si procedeu de preparare al acestuia;
OSIM patent nr.127719: Crema fotochemoprotectoare si procedeu de preparare a acesteia.
 
Publicatiile cele mai importante: Articole:
1. Protective effect of a Calluna vulgaris extract against UVB-induced phototoxicity in HaCaT human immortalized keratinocytes, Perde-Schrepler M, Chereches G, Brie I, Virag P, Barbos O, Soritau O, Tatomir C, Fischer-Fodor E, Filip A, Vlase L, Postescu ID, J.Environmental Pathology, Toxicology and Oncology, 2011, 30(4): 323-331, Impact Factor: 1,107
2. Modulation of Doxorubicin Induced Oxidative Stress by a Grape (Vitis Vinifera L.) Seed Extract in Normal and Tumor Cells; I.D. Postescu, G. Chereches, et al;J.Med. Food. 15(7), 2012, 639-645
3. Grape seed extract as photochemopreventive agent against UVB- induced skin cancer. Maria Perde-Schrepler, Gabriela Chereches, Ioana Brie, Corina Tatomir, Ion Dan Postescu, Loredana Soran, Adriana Filip, J.Photochem.Photobiol.B, 2013, 118: 16–21. Impact Factor: 3.110
4. Anticancer and Antimicrobial Activities of Some Antioxidant Rich Tamokou JdD, Chouna JR, Fischer-Fodor E, Chereches G, et al; Cameroonian Medicinal Plants.(2013)PLoSONE,8(2):e55880
5. Metformin plus sorafenib highly impacts temozolomide resistant glioblastoma stem-like cells; Aldea MD, Petrushev B, Soritau O, Tomuleasa CI, Berindan-Neagoe I, Filip AG, Chereches G, et al; J.Buon,19(2),2014,502-511
6. Comparative in vitro study regarding the biocompatibility of titanium-base composites infiltrated with hydroxyapatite or silicatitanate; Ioana-Carmen Brie, Olga Soritau, Noemi Dirzu, C.Berce, Adriana Vulpoi, C.Popa, Milica Todea, S.Simon, Maria Perde-Schrepler, Piroska Virag, Otilia Barbos, Gabriela Chereches, et al; J. of Biol.Engineering 8:14,2014,1-19

7. Synthesis of structural analogues of hexadecylphosphocholine and their antineoplastic, antimicrobial and amoebicidal activity; Lukas Timko, Eva Fischer-Fodor, Maria Garajova, Martin Mrva, Gabriela Chereches, et al; Europ.J.of Medicinal Chem.,93,2015, 263-273

8. Novel Strategies for the Improvement of Stem Cells Transplantation in Degenerative Retinal Diseases; Simona Delia Nicoara, S. Susman, Oana Tudoran, Otilia Barbos, Gabriela Chereches, et al; Stem Cells Intern,2016, Article ID 1236721, 1-9

9. Biomarkers for the early detection of relapses in metastatic colorectal cancers; Gabriela Chereches1*, Otilia Barbos1*, Rares Buiga1 et al; JBUON 2017; 22(3): 658-666

10. Circulating Tumor Cells in Minimally Invasive Follicular Thyroid Carcinoma and Benign Thyroid Tumors with a Follicular Pattern: Pilot Experience; C.I Badulescu, R.J.Marlowe, A.Piciu, R. Buiga, O. Barbos, N.I. Bejinariu, G.Chereches et al; Acta Endocrinologhica (Buc),2018, vol XIV,no.1,1-10